Versed medication8/2/2023 ![]() ![]() Midazolam is a federally controlled substance (Schedule IV) as it has a risk of abuse, misuse, and addiction, which can lead to overdose or death. Get emergency help right away if you experience shallow or slowed breathing, breathing stops (which may lead to the heart stopping), or excessive sleepiness (sedation). a light-headed feeling, like you might pass out.restlessness or you feel agitated or irritable.Tell your healthcare provider right away if you have: If you are administered midazolam nasal spray, your healthcare providers will watch you for symptoms such as weak or shallow breathing. Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other central nervous system depressants as they also may slow your breathing. Use with opioids or other central nervous system depressants Further, as midazolam nasal spray is administered while directly under the care of a healthcare provider, adverse effects may more easily be managed. Midazolam nasal spray is approved by the FDA because the benefits of arresting status epilepticus outweigh the risks. While it may not be possible in an emergency setting to communicate with your healthcare providers, preparation can overcome this barrier. The treatment of status epilepticus requires observation and management of vital functions by healthcare providers within the emergency setting. Especially tell your healthcare provider if you take: opioids, drugs that cause sleepiness or dizziness, or alcohol.Īs status epilepticus is a potentially life-threatening condition associated with a high risk of permanent neurological impairment, there may be occasions where the use of midazolam is required despite the risks of serious adverse events. Do not start or stop other medicines without talking to your healthcare provider. ![]() Taking midazolam with certain other medicines may cause side effects or affect how well they work. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. You should not stop using midazolam suddenly unless your healthcare provider tells you to stop the medicine because of a serious side effect. What is important to know about taking midazolam?ĭo not stop taking midazolam suddenly unless directed to do so by your healthcare provider.Īs with all antiseizure medications, midazolam should be withdrawn gradually to minimize the risk of causing or worsening seizures or status epilepticus. are breastfeeding or plan to breastfeed.are pregnant or plan to become pregnant.have a history of drug or alcohol abuse.have asthma or other breathing disorders.have a history of depression, mood problems, or suicidal thoughts or behavior.If possible, tell your healthcare provider if you: Other considerations may influence whether you should take midazolam. Patients with acute narrow-angle glaucoma should not take midazolam. If you are allergic to midazolam or any other benzodiazepines (alprazolam, diazepam, clonazepam, clobazam), or if you have a known sensitivity to polyethylene glycol, propylene glycol, or benzyl alcohol, then you should not take it. It is also available as an oral solution that is not indicated for epilepsy treatment. Midazolam is available as a solution for a nasal route only and is administered by a healthcare provider for no more than 2 doses in an emergency setting. How can you take midazolam? (Available formulations) For more information, please see the prescribing information. Based on their judgment and knowledge, a drug may be prescribed for situations not included in the indications. Your epilepsy treatment should always be discussed with your healthcare provider before use. These treatments are meant to rapidly stop seizures, whether to prevent an emergency or during one while under the care of healthcare providers. Benzodiazepines are commonly used in epilepsy on an “as needed” basis as a rescue medicine. ![]() Midazolam is a member of a group of drugs known as benzodiazepines. Midazolam (my DAZ oh lam) has been approved by the FDA for the acute treatment of intermittent, stereotypic episodes of frequent seizure activity (i.e., seizure clusters, acute repetitive seizures) that are distinct from a patient’s usual seizure pattern in patients with epilepsy 12 years of age and older (nasal spray only). ![]()
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